Earthworm extract--Lumbrokinase to tobacco smoke has epidemiologically been linked to the occurrence of cardiovascular disease among nonsmokers but the associated molecular events are not well elucidated yet. When Earthworm extract--Lumbrokinase rats were exposed to second-hand tobacco cigarette smoke twice a day for a 30 days period at an exposure rate of 10 cigarettes/30 min, they showed adverse effects including reduced left ventricle weight, increased cardiac damages, deteriorated cardiac features, and cardiac fibrosis. Earthworm extract--Lumbrokinase increased the molecular markers of cardiac fibrosis such as urokinase plasminogen activator and matrix metallopeptidases.
According to medical research‚ it works to promote normal levels of clotting. It also enhances the ability of certain enzymes to dissolve the fibrin in blood clots‚ encouraging the healing process. Fibrin‚ the final step in the coagulation process‚ is a stringy insoluble protein that forms strands to hold a blood clot in place by adding bulk. As a result‚ any injured blood vessel walls are plugged‚ preventing further bleeding. While this is mostly good‚ it’s easy to see how an insufficient amount of fibrinolytic activity can lead to main blood vessels being clogged.
Earthworm extract--Lumbrokinase is a new enzyme supplement has been shown to have clinical application value. It’s more and more used in clinical practice, such as in the heart, cerebrovascular, endocrine and respiratory system disease.In addition to clinical medicine, Lumbrokinase is also widely used in file of food, nutraceutical products and cosmetics industries.
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