Lumbrokinase Powder is an important fibrinolytic enzyme derived from earthworm. The capsules of the pastafoods have been widely used. Unfortunately, the life cycle of earthworm is long, and extraction of lumbrokinases is generally a labor intensive and time- Is often contaminated by multiple components. The successful expression of the recombinant provided a way to obtain single component with fibrinolytic activity. Meanwhile, it was reported that could be orally administered. Therefore, we have been attempting to produce recombinant using a safe and cost- Effective yield system. In this stduy, gene placed under the seed-specific promoter, napA, was expressed in the. The yield of was about 5.1 g / kg sunflower seeds as determined by. Fibrin plate assays revealed that the crude extraction of rom sunflower Seed kernel contained a high level of fibrinolytic activity. Following oral administration of T1 generation of transgenic sunflower seed kernel, The prothrombin time, the activated partial thromboplastin time, the thrombin time and the carrageenin-induced thrombosis were evaluated, using mice as the thrombosis model. It was put that the oral treatment of mice with transgenic sunflower seed kernel had a significant anti-thrombotic effect . The finding provides a way for low-cost and seed kernel edible delivery of human therapeutic proteins.

Glucocorticoids have a moderating effect on a variety of organs, and their regulatory effects are affected by a variety of factors such as the concentration of glucocorticoids, the type of receptor, the type of target cells and the stage of differentiation. For immune cells, the role of hormones is also associated with the length of time the cells are exposed to the antigen. At the same time, other hormones or regulatory factors can also affect the role of glucocorticoids.

A higher organism with organ systems that have been structurally and functionally differentiated must be able to coordinate the biochemical processes within and between the organs or cells, and even if the environmental conditions are rapidly changing The Hormones play an important role in the regulation process; they promote many metabolic reactions and differentiation processes, and the rate at which they function can vary widely. Some hormones act almost instantaneously by activating adenylate cyclase to cause the production of adenosine 3 ', 5'-monophosphate (cyclized AMP), and cyclization of AMP (second messenger) Vigor to transfer hormone information to intracellular metabolism. Delayed role of hormones, mainly morphological hormones, the first role in the nucleus, in the nucleus through the activation of genes to induce the synthesis of certain enzymes.

Lumbrokinase Powder is a new enzyme supplement has been shown to have clinical application value. It’s more and more used in clinical practice, such as in the heart, cerebrovascular, endocrine and respiratory system disease.In addition to clinical medicine, Lumbrokinase is also widely used in file of food, nutraceutical products and cosmetics industries.