Lumbrokinase from the earthworm Lumbricus bimastus has been identified. The is composed of Earthworm extract--Lumbrokinase and includes an open reading frame that encodes two parts of the protein: a signal peptide of 44 amino acids and a mature peptide of residues. The of exhibits a high degree of sequence identity with other lumbrokinase genes, ranging from 87.6% (F-III-I) to 98.3% (EFE-3). The gene encoding the native form of, with a 5' non-functional end removed, was obtained by amplification and was sub-cloned into Earthworm extract--Lumbrokinase, a yeast expression and secretion vector. Earthworm extract--Lumbrokinase and Western blot analyses showed that secreted into the culture medium was specifically recognized by the wild type lumbrokinase polyclonal antibody and was able to dissolve artificial fibrin plates.

The only fully researched oral fibrinolytic supplement on the market. This is the process that prevents blood clots from growing. Beneficial for any illness that has an accompanying hypercoagulable blood state, shown to be present in many chronic illnesses. Recommended for some on hormone replacement therapy or birth control pills, and some who can’t tolerate standard preventative pharmaceutical drugs.

Lumbrokinase is a group of six enzymes that come from the digestive systems of the Red Wriggler or Red Marsh species of earthworm called Lumbricus, most commonly found in apple orchards. It has recently been added to protocol lists in the natural treatment of Lyme Disease. These enzymes have been shown to help dissolve fibrin. Fibrin is a protein substance released by the body in the healthy formation of blood clots.

Earthworm extract--Lumbrokinase is a new enzyme supplement has been shown to have clinical application value. It’s more and more used in clinical practice, such as in the heart, cerebrovascular, endocrine and respiratory system disease.In addition to clinical medicine, Lumbrokinase is also widely used in file of food, nutraceutical products and cosmetics industries.

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Earthworm extract--Lumbrokinase